Internationally recognized research centres and market-leading medical technology companies have been cooperating via the RHINODIAGNOST.eu project to establish coordinated morphological and functional diagnostics for ENT physicians. RHINODIAGNOST services aim to provide additional decision aids, such as 3D models and flow simulations, for ENT physicians and radiologists. The applied functional diagnostics make use of medical image data that are fully automatically pre-processed using machine learning methods to run numerical simulations of respiratory flows on high-performance computers.